BTY 604: Bioprocess Engineering | 6 credits (40-5-15) |
Objectives
To enable students bridge the gap between theoretical concepts and practical aspects in industrial settings.
Contents
Introduction to Bioprocess Engineering, Bioreactors and Membrane Bioreactors, Isolation Preservation and Maintenance of Industrial Microorganisms, Kinetics of microbial growth and death, Media and medical sterilization for Industrial Fermentation, Air quality Management and Air sterilization, Types of fermentation processes. Analysis of batch, Feed batch and continuous bioreactors, stability of microbial reactors, analysis of mixed microbial populations, specialized bioreactors (pulsed fluidized, photobioreactors etc). Fermentation kinetic and monitoring, Measurement and control of bioprocess parameters; Downstream processing: Introduction, Removal of microbial cells and solid matter, foam reparation, precipitation, filtration, centrifugation, cell disruptions, liquid-liquid extraction. Chromatography, membrane process; Drying and crystallization, Effluent treatment D.O.C. and C.O.D. treatment and disposal of effluents; Whole cell immobilization and their industrial applications. Bioconversion and Biotransformation.
Industrial Production of chemicals, biochemicals, biological and services: examples Alcohol (ethanol). Acids (citric, acetic and gluconic), Solvents (glycerol, acetone, butanon), Antibiotics (penicillin, streptomycinl, tetracy6cline), microlodes, anticancer antibiotic, Amino acids (lysine, glutamic acid), Single Cell Protein, single Cell Lipids. Use of microbes in mineral beneficiation and oil recovery; Introduction to Food technology; elementary idea of canning and packing; Fat-Based Edible products; Sterilization and Pasteurization of food Products; Nutraceuticals; Technology of Typical food products (bread, cheese, idli, Agro-products (oilseeds); Food preservation; Food colors, Flavors, and antioxidants; Hydrogenation, oxidation, esterification, polymerization; Fine Chemicals (e.g. Biosurfactants); spirulina, yeast, oleo chemicals (fatty acids, glycerol, methol-petrochemicals; perfumery chemicals; drugs and pharmaceuticals).