Faculty of Science

Objectives

To introduce the student to the fundamental chemical and biological concepts that underlie the discipline of pharmacology and rational therapeutics and will focus on the molecular basis of drug action.

Contents

Mechanisms of drug action (including receptor site theory, antimetabolite theory, enzyme inhibition) and determinants of drug activity (such as physicochemical properties); fundamental concepts in drug design (bioisosterism, structure-activity relationships, drug latentiation; mechanisms of drug resistance, drug allergy, drug tolerance and physical dependence, chemical mutagenesis, carcinogenesis and teratogenesis.

Prerequisite:

Co-registration: