MBP608: Validity and Reliability of Diagnostic and Screening Tests 6 credits (20-20-20)

Objectives

To teach students how to assess the quality of newly available screening and diagnosis tests to make reasonable decisions about their use and interpretation

Contents

Biologic variation of human populations, Validity of screening tests, tests with dichotomous results (Positive or Negative), tests of continuous variables; use of multiple tests: sequential(two-stage) testing, simultaneous testing; net sensitivity using two simultaneous tests, net specificity using two simultaneous tests, Comparison of Simultaneous and sequential testing, Predictive value of a test; Relationship between Predictive value and Disease prevalence; Reliability (repeatability) of tests; Relationship between validity and Reliability