Faculty of Science

Objectives

To provide an introduction to the fundamental biochemical and physico-chemical principles underlying drug action with a broad coverage of the manifestations of chemical reactivity which result in specific biochemical events that collectively lead to drug action.

Contents

Historical aspects of pharmacotherapy; structural properties and biologic activity; basic mechanisms and concepts of drug action (e.g., phases of drug action, modern theories of drug action, including intrinsic activity, agonists and antagonists, occupancy and frequency theories, etc); signal transduction; drug latentiation; and structure-activity relationships.