CHM314: Analytical and Instrumental Methods 6 credits (40-10-10)

Objectives

To emphasize the treatment of experimental data, highlight the basic principles of chromatography and electroanalytical methods.

Contents

Statistical treatment of experimental data: precision and accuracy; errors; population and sampling: mean, variance, standard deviation; Gaussian distribution; confidence limits, method of least squares; Electroanalytical methods: cells, electrodes and electrode potentials; potentiometry: reference, indicator electrodes, instruments for measuring cell potentials; potentiometric titrations; coulometry; voltammetry: signals, instrumentation and types; polarography; Introduction to separation methods; Chromatography – basic principles; gas chromatography: chromatograph; gas-liquid chromatography; gas-solid chromatography. Liquid Chromatography; High-Performance Liquid Chromatography (HPLC): HPLC instrument; partition chromatography; adsorption chromatography; ion-exchange chromatography; size exclusion chromatography; thin-layer chromatography; supercritical fluid chromatography (SFC) and extraction; overview of capillary electrophoresis.

Prerequisite:

CHM201