Faculty of Science

Objectives

To cover the regulation of gene expression during development in several model systems and highlight the diverse molecular mechanisms used to control gene expression as well as the conservation of basic strategies to generate different developmental states.

Contents

Mechanisms controlling developmental switches between alternative pathways, mechanisms for generating specialised cell types (e.g. muscles and neurons); the role of transcription factors in regulating the spatial organisation of the embryo; The mechanisms by which development is regulated by extra-cellular signals, Lysogeny or Lysis in -Phage Infection of E.coli; Cell-Type Specification and Mating-Type Conservation in Yeast; Myogenesis in Mammals; Neurogenesis in Drosophila and Mice; Regional Specification during Drosophila Embryogenesis; Mammalian Homologs of Drosophila ANT-C and BX-C.