Faculty of Science

Objectives

The objectives of this course are to provide students with advanced knowledge and understanding of parasitology, bacteriology, virology and immunology.

Contents

The course uses the knowledge about infectiology, and expands on the immunological responses to human infection. Topics include:

1. Haematopoiesis, T-cell and innate responses and anti-viral immunity

2. Innate immunity - TLR, NLR and RLR

3. Cell-mediated immunity from viruses - pDC, CD8+ cytotoxic T cells

4. The humoral immune response - B cell activation and maturation, functions of immunoglobulin isotypes, destruction of antibody-coated pathogens

5. T cell-mediated immunity - Antigen-priming of naive T cells by DCs, properties of effector T cells, CD4+ T helper cells (Th1, Th2, Th17, Tregs)

6. Autoimmunity - Breaking of self-tolerance mechanisms, pathogenetic mechanisms, genetic and environmental basis of autoimmunity