BCH604: Advanced Nucleic Acid Chemistry 6 credits (40-10-10)

Objectives

To describe the structure and dynamics of nucleic acids in relation to their function.

Contents

Structure of DNA and RNA; Gene organisation in the chromosomes; Interactions between DNA and proteins; Gene expression and regulation; Mechanisms of cell differentiation, proliferation, apoptosis (cell-death), and cancer; Study of original articles and critical reviews; Nucleic acid sequence databases; Sequencing methods.